About the Journal
International Open Access Journal of Genetic, Genomic and Molecular Cardiovascular Medicine and Surgery
‘Genomic and Molecular Cardiology’ (GMC) is the open-access online journal publishing original research, meta-analyses, reviews, case commentaries and independent reports on recent developments focusing on genetic, genomic and molecular aspects of wide ranging diverse cardiovascular conditions. The journal particularly focuses on, but not limited to, the delineation of clinical phenotypes related to new genes & mutations, pathogenic evidence for genomic variants, gene-molecular families; genotype-phenotype correlations; basic and clinically applied molecular genetics; advances in next generation sequencing and new cardiac therapeutic and interventional developments.
The GMC journal encourages original OMICS related cardiovascular research (proteomics, transcriptomics, metabolomics, functional genomics and systomics etc.), molecular basis of the clinical cardiology practice and new therapeutic advances including clinical trials in the burgeoning field of pharmacogenomics and personalized/ stratified precision medicine related to cardiovascular medicine and surgery. The journal also features current and comprehensive reviews in the areas of recent advances in cardiovascular development, Mendelian cardiovascular disorders, polygenic/ multifactorial complex diseases (hypertension and ischemic heart disease etc.), new diagnostic and therapeutic progress, and controversies in molecular cardiovascular medicine and surgery. A dedicated news section summarizes the new developments highlighting articles and reports likely to impact the management of cardiovascular disorders. Other features include clinical case reports and studies, book reviews, and letters to the editor.
The following categories (not restricted to) of original papers and articles are published in ‘Genomic & Molecular Cardiology’–
- Genomic and molecular aspects of Cardiovascular development
- Congenital heart disease including the adult Congenital heart disease
- Inherited cardiomyopathies: Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Arryhthmogenic right ventricular cardiomyopathy (ARVC) and left ventricular non-compaction (LVNC)
- Cardiovascular ‘gene-molecule’ groups: – Sarcomere, cytoskeletal, junctional, nuclear envelope, notch signaling, RAS_MAPK, ion channel proteins and many others
- Inherited arrhythmias- Long QT Syndrome (LQTS); Short QT Syndrome, Brugada syndrome, Catecholaminergic polymorphic ventricular tachycardia (CPVT) and Early Repolarisation syndrome.
- Inherited vascular/ connective diseases: Marfan syndrome, Loeys-Dietz syndrome, Ehlers-Danlos syndrome and other connective tissue diseases with cardiovascular phenotypes
- Hypertension- systemic and pulmonary arterial
- Inherited metabolic disease with cardiovascular phenotypes
- Sudden unexplained/cardiac death (infant and adult)
- Inherited neuromuscular disorders with cardiovascular phenotypes
- Complex cardiovascular disease (coronary artery disease; hypertension)
- Chronic inflammatory and auto-immune cardiovascular conditions
- Molecular cardiology- diagnostic, experimental, applied and translational
- Cardiovascular pharmacogenetics & pharmacogenomics
- Cardiovascular personalized and precision medicine
- Bio-banking and cardiovascular genomic/ molecular databases
- Gene, Stem cell and somatic cell therapy in cardiovascular diseases
- Surgical and non-invasive therapy for inherited cardiovascular conditions
- Education and training in cardiovascular genetics and molecular medicine
- Ethical, legal, social issues related to genetic and molecular practice of cardiovascular medicine and surgery
