Genomics and Molecular Cardiology

International Open Access Journal of Genetic, Genomic and Molecular Cardiovascular Medicine and Surgery

‘Genomic and Molecular Cardiology’ (GMC) is the open-access online journal publishing original research, meta-analyses, reviews, case commentaries and independent reports on recent developments focusing on genetic, genomic and molecular aspects of wide ranging diverse cardiovascular conditions. The journal particularly focuses on, but not limited to, the delineation of clinical phenotypes related to new genes & mutations, pathogenic evidence for genomic variants, gene-molecular families; genotype-phenotype correlations; basic and clinically applied molecular genetics; advances in next generation sequencing and new cardiac therapeutic and interventional developments.

The GMC journal encourages original OMICS related cardiovascular research (proteomics, transcriptomics, metabolomics, functional genomics and systomics etc.), molecular basis of the clinical cardiology practice and new therapeutic advances including clinical trials in the burgeoning field of pharmacogenomics and personalized/ stratified precision medicine related to cardiovascular medicine and surgery. The journal also features current and comprehensive reviews in the areas of recent advances in cardiovascular development, Mendelian cardiovascular disorders, polygenic/ multifactorial complex diseases (hypertension and ischemic heart disease etc.), new diagnostic and therapeutic progress, and controversies in molecular cardiovascular medicine and surgery. A dedicated news section summarizes the new developments highlighting articles and reports likely to impact the management of cardiovascular disorders. Other features include clinical case reports and studies, book reviews, and letters to the editor.
The following categories (not restricted to) of original papers and articles are published in ‘Genomic & Molecular Cardiology’

  • Genomic and molecular aspects of Cardiovascular development
  • Congenital heart disease including the adult Congenital heart disease
  • Inherited cardiomyopathies: Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Arryhthmogenic right ventricular cardiomyopathy (ARVC) and left ventricular non-compaction (LVNC)
  • Cardiovascular ‘gene-molecule’ groups: – Sarcomere, cytoskeletal, junctional, nuclear envelope, notch signaling, RAS_MAPK, ion channel proteins and many others
  • Inherited arrhythmias- Long QT Syndrome (LQTS); Short QT Syndrome, Brugada syndrome, Catecholaminergic polymorphic ventricular tachycardia (CPVT) and Early Repolarisation syndrome.
  • Inherited vascular/ connective diseases: Marfan syndrome, Loeys-Dietz syndrome, Ehlers-Danlos syndrome and other connective tissue diseases with cardiovascular phenotypes
  • Hypertension- systemic and pulmonary arterial
  • Inherited metabolic disease with cardiovascular phenotypes
  • Sudden unexplained/cardiac death (infant and adult)
  • Inherited neuromuscular disorders with cardiovascular phenotypes
  • Complex cardiovascular disease (coronary artery disease; hypertension)
  • Chronic inflammatory and auto-immune cardiovascular conditions
  • Molecular cardiology- diagnostic, experimental, applied and translational
  • Cardiovascular pharmacogenetics & pharmacogenomics
  • Cardiovascular personalized and precision medicine
  • Bio-banking and cardiovascular genomic/ molecular databases
  • Gene, Stem cell and somatic cell therapy in cardiovascular diseases
  • Surgical and non-invasive therapy for inherited cardiovascular conditions
  • Education and training in cardiovascular genetics and molecular medicine
  • Ethical, legal, social issues related to genetic and molecular practice of cardiovascular medicine and surgery

Editorial board

Editor in Chief: Professor Dhavendra Kumar, MD DSc FRCP FACMG
Institute of Medical Genetics, University Hospital of Wales, Cardiff University School of Medicine, Cardiff, UK


Professor Perry Elliott, MD FRCP FACC
Director/ Hon. Consultant- Inherited Heart Diseases Unit, St. Bart’s Hospital, London School of Medicine & Dentistry, Queen Mary University of London & Director- Centre for Cardiovascular Genetics, University College London, UK
Dr. Dan E Arking, Professor, Nathan-Mckusick Institute of Genetic Medicine, Johns Hopkins, Baltimore, USA
Professor Ajay Bahl, Department of Cardiology, Postgraduate Institute of Medical and Research, Chandigarh, India

Board Members:

Professor Silvia G. Priori, MD
Professor of Medicine, New York University School of Medicine; Director, Cardiovascular Genetics Program; Professor of Cardiology, University of Pavia (Italy)
Professor Arthur Wilde, Director- Molecular Cardiology laboratory, Academic Medical Center, Amsterdam, The Netherlands
Professor Julie de Backer, Consultant and Head of Medical Genetics, University Hospital of Ghent, University of Ghent, Belgium
Professor Bart Loeys, Director- Cardiovascular Genetics, University of Antwerp, Belgium
Dr. Elijah Behr, Department of Cardiovascular Medicine, St George’s Hospital Medical School, London, UK
Professor Pier Lambiase, Hon. Consultant- Inherited Heart Diseases Unit, St. Bart’s Hospital, London School of Medicine & Dentistry, Queen Mary University of London & Centre for Cardiovascular Genetics, University College London, UK
Professor Kate Bushby, Institute of Human Genetics & Life, Newcastle upon Tyne, UK
Professor Robert Hinton, Department of Pediatric Cardiology, Indiana University Medical Center, Cincinnati, USA
Dr. Lorenzo Monserrat, HealthinCode, Coruna University Hospital, La Coruna, Spain
Professor Madhu Khullar, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Dr. Ramon Brugada, Department of Cardiology, University of Girona, Spain; New York, USA
Professor Clifford Garratt, Department of Cardiology, University of Manchester, UK
Dr. Duncan Cole, Department of Laboratory Medicine, University Hospital of Wales, Cardiff, UK
Dr. Sarah Bowdin, Department of Genetics, Hospital for Sick Kids, Toronto, Canada
Dr. Matthew Daniels, Department of Cardiovascular Medicine, University of Oxford, UK
Professor Michael Christiansen, Statens Serum Institute, Copenhagen, Denmark
Professor Sanjay Sharma, Department of Cardiovascular Medicine, St George’s Hospital Medical School, London, UK
Professor Eloisa Arbustini, Centre for Inherited Cardiovascular Diseases and Molecular Genetic Laboratory, IRCCS Policlinico San Matteo, Pavia, Italy
Professor Mary Sheppard, Department of Cardiovascular Pathology, Cardiovascular Science Centre, St George’s Hospitla Medical School, London, UK
Ms. Sharon Jenkins, Sr. Genetic Counsellor- Inherited Heart Diseases Unit, St. Bart’s Hospital, London School of Medicine & Dentistry, Queen Mary University of London, UK
Professor Ulrich von Oppel, Department of Cardiothoracic Surgery, University Hospital of Wales, Cardiff, Wales, UK
Dr. Zahurul Alam Bhuiyan, Director Molecular Genetics Laboratory, Lausanne, Switzerland
Dr. Anne Mieke Aartsma-Rus, Department of Human Genetics, Center for Human and Clinical Genetics, Leiden University Medical Center, The Netherlands
Professor Viji Samuel, Department of Cardiology, Christian Medical College, Vellore, Tamil Nadu, India
Professor Zaheer Yousef, Department of Cardiology, University Hospital of Wales, Cardiff University School of Medicine, Cardiff, UK

Submission of manuscripts:

Manuscripts of original research papers, review articles, commentaries and opinions and conference reports are invited for publication in Genomic and Molecular Cardiology. All manuscripts should be submitted online as an email attachment to Only commonly used word processing software should be used for example Microsoft Word, Adobe, Rich Text etc.

All manuscripts should follow the usual format and include: the title, authors, institute affiliations, name/address of the corresponding author, selection of search engine key words (not more than 10), name/ address of relevant ethical approval authority, declaration on conflict of interest, statement on commercial/ financial benefits and copyright authorization for any illustrations, tables or part of the text included in the manuscript. References should be cited in the text with author and year; use suffix et al for more than 2 authors in the reference cited. All references should be listed in alphabetical order. Name of the soft ware reference manager should be indicated in the manuscript.

All manuscripts are independently peer-reviewed and final decision is made by the editor in chief reflecting views of the lead- editor (usually a member of the editorial board or a guest editor) and external reviewers. One of the following decisions will be notified to the corresponding author-

Accept; Accept subject to major revision; Accept subject to minor revision; Reject without peer review; Reject following peer review

All accepted manuscripts are published online subject to copyright agreement with the publisher and payment of open access charge, advised with the copyright instructions. The open-access may be waived on the recommendation of the editor in chief. The open access tariff is available on request, however the specific amount will be advised on acceptance of the manuscript. All open access paid published material will become globally accessible. However, an individual reader, organization or Institution may access the non-paid publication subject to a small downloading fee advised at the time of consumer registration.

Corporate information:

‘Genomic and Molecular Cardiology’ is published by The Genomic Medicine Foundation (UK) Ltd, a not-for-profit company registered in England and Wales (Registered Number 8749919). The publisher holds all legal rights and acquires all financial or any other benefits of any published material in the journal. For all enquiries and information please visit or contact direct the Editor in Chief (